Detalhe da pesquisa
1.
A hydride transfer complex reprograms NAD metabolism and bypasses senescence.
Mol Cell
; 81(18): 3848-3865.e19, 2021 09 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34547241
2.
Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells.
Mol Cell
; 79(5): 846-856.e8, 2020 09 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32755594
3.
MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors.
iScience
; 27(3): 109188, 2024 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38433910
4.
The mitochondrial pyruvate carrier complex potentiates the efficacy of proteasome inhibitors in multiple myeloma.
Blood Adv
; 7(14): 3485-3500, 2023 07 25.
Artigo
Inglês
| MEDLINE | ID: mdl-36920785
5.
Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells.
FEBS Open Bio
; 12(5): 959-982, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35302710
6.
Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAFV600 melanoma.
Nat Commun
; 13(1): 1100, 2022 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35232962
7.
Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids.
Cell Rep
; 40(7): 111198, 2022 08 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35977476
8.
The role of GSK3 in metabolic pathway perturbations in cancer.
Biochim Biophys Acta Mol Cell Res
; 1868(8): 119059, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33989699
9.
Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin.
Neoplasia
; 23(4): 391-399, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33784591
10.
Cancer Plasticity: The Role of mRNA Translation.
Trends Cancer
; 7(2): 134-145, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33067172
11.
Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK.
Dev Cell
; 56(12): 1756-1769.e7, 2021 06 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34022133
12.
Methotrexate elicits pro-respiratory and anti-growth effects by promoting AMPK signaling.
Sci Rep
; 10(1): 7838, 2020 05 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32398698
13.
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer.
Nat Commun
; 11(1): 3701, 2020 07 24.
Artigo
Inglês
| MEDLINE | ID: mdl-32709883
14.
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis.
Nat Commun
; 11(1): 3520, 2020 07 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32665551
15.
mTOR as a central regulator of lifespan and aging.
F1000Res
; 82019.
Artigo
Inglês
| MEDLINE | ID: mdl-31316753
16.
PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs.
Cell Metab
; 26(5): 778-787.e5, 2017 Nov 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28988825
17.
The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer.
Cell Rep
; 14(4): 920-931, 2016 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-26804918
18.
PGC-1α supports glutamine metabolism in breast cancer.
Cancer Metab
; 1(1): 22, 2013 Dec 05.
Artigo
Inglês
| MEDLINE | ID: mdl-24304688